Micaiah Achtymichuk’s 3rd blog: Tuesday; March 30, 2010 3/3.
What we did today: in today’s class we…
- Did a pop quiz on the cell cycle.
- Discussed the yesterday homework questions.
- Talked about mitosis technology- cloning/ in vitro fertilization.
- Labeled microphotographs of cell division,
- Read and discussed cell aging (pages: 562- 563 and 570.)
- Drew a stick figure diagram of IVF vs. Cloning.
- Finished the day with an assignment on the cell cycle and cancer cells.
- (Onion root tip assignment can be found here: http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/cell_cycle.htm)
(IVF & Cloning diagram)
Thoughts about the material:
I found the Section on the cell clock very interesting, and I attempted to find more information on this Mechanism.
Above and beyond:
On my quest to find answers to my question I was side tracked by an interesting article about the connection between circadian rhythm (a roughly 24-hour cycle in the biochemical, physiological or behavioral processes of living entities) and cell division within organisms, so I posted it instead. The study focused on Bacteria.
"We looked at how the biological clock controls when bacterial cells divide -- in bacteria, there's a period of four hours where the cells are not allowed to divide -- and we identified the structural changes in a key protein that controls this action."
The scientists probed cell division in the cyanobacterium Synechococcus elongatus.
“They found that the timing of cell division, patterns of gene expression and compaction of the chromosome are controlled by the circadian clock. What was unknown was precisely how the circadian clock in bacteria controlled cell division. Using time-lapse microscopy, Golden and her colleagues discovered that the clock proteins KaiA, KaiB, and KaiC in bacteria control the action of a key protein called FtsZ, preventing it from going to the middle of the cell and forming a ring necessary for cell division. After four hours has elapsed, the clock proteins allow FtsZ to move toward the center of the cell and change structurally to form this ring.
"This complex of proteins is at the heart of the bacterial clock controlling cell division," said Golden. "There are two cycles, the cell cycle and the circadian cycle, that need to mesh for organisms to function. What we learned from this study is how these two cycles with different timing periods interact, and that the mechanisms that control the timing of cell division in bacteria are different than they are in eukaryotic cells."
Golden added that knowledge of the mechanisms of how organisms from bacteria to humans control the timing of their cell division and other processes has application to many human problems resulting from disorders in the circadian clock.